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| Name | Pos | Team | Age | DOB | POB | Nationality | Bats | Throws | Height | Weight | Salary |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Sacco Jr., Tommy | SS | Sugar Land Space Cowboys | 25 | 05/21/1999 | Chandler | USA | Switch | Right | 5' 10" | 195 lbs | - |
| Salazar, Cesar | C | Sugar Land Space Cowboys | 28 | 03/15/1996 | Hermosillo | MEX | Left | Right | 5' 8" | 200 lbs | - |
| Sanabria, Romeo | 1B | El Paso Chihuahuas | 22 | 05/02/2002 | Miami | USA | Left | Right | 6' 3" | 200 lbs | - |
| Sanchez, Fernando | RP | El Paso Chihuahuas | 24 | 09/13/2000 | Obregón | MEX | Left | Left | 6' 0" | 200 lbs | - |
| Sanchez, Juan | RP | Sacramento River Cats | 24 | 11/12/2000 | Valencia | VEN | Left | Left | 6' 2" | 165 lbs | - |
| Sanchez, Yolmer | 2B | Free Agent | 32 | 06/29/1992 | Maracay | VEN | Switch | Right | 5' 9" | 210 lbs | - |
| Santos, Pedro | RP | Las Vegas Aviators | 25 | 01/07/2000 | Trinidad | CUB | Right | Right | 6' 4" | 220 lbs | - |
| Sasaki, Roki | SP | Oklahoma City Comets | 23 | 11/03/2001 | Iwate | JPN | Right | Right | 6' 2" | 185 lbs | - |
| Sauer, Matt | RP | Oklahoma City Comets | 26 | 01/21/1999 | Santa Maria | USA | Right | Right | 6' 4" | 230 lbs | - |
| Saul, Eli | RP | Reno Aces | 23 | 08/16/2001 | Vancouver | CAN | Left | Right | 6' 5" | 215 lbs | - |
| Schunk, Aaron | 3B | Albuquerque Isotopes | 27 | 07/24/1997 | Atlanta | USA | Right | Right | 6' 2" | 205 lbs | - |
| Seig, Hayden | RP | Salt Lake Bees | 26 | 09/10/1998 | Mechanicsburg | USA | Right | Right | 6' 5" | 225 lbs | - |
| Seymour, Carson | RP | Sacramento River Cats | 26 | 12/16/1998 | Temecula | USA | Right | Right | 6' 5" | 260 lbs | - |
| Shaw, Evan | RP | Oklahoma City Comets | 24 | 02/02/2001 | Fridley | USA | Left | Left | 6' 4" | 205 lbs | - |
| Sheets, Gavin | 1B | El Paso Chihuahuas | 28 | 04/23/1996 | Timonium | USA | Left | Left | 6' 5" | 235 lbs | $740,000 |
| Shenton, Austin | 1B | Tacoma Rainiers | 27 | 01/22/1998 | Bellingham | USA | Left | Right | 6' 0" | 205 lbs | - |
| Short, Avery | RP | Reno Aces | 24 | 03/14/2001 | Indianapolis | USA | Right | Left | 6' 1" | 205 lbs | - |
| Short, Zack | SS | Sugar Land Space Cowboys | 29 | 05/29/1995 | Kingston | USA | Right | Right | 5' 10" | 180 lbs | - |
| Simmons, Kendall | 2B | Oklahoma City Comets | 24 | 04/11/2000 | Macon | USA | Right | Right | 6' 0" | 180 lbs | - |
| Sinacola, Nick | SP | Sacramento River Cats | 25 | 10/29/1999 | Providence | USA | Left | Right | 6' 2" | 205 lbs | - |
| Skipper, Carson | RP | Albuquerque Isotopes | 25 | 08/12/1999 | Trussville | USA | Left | Left | 6' 2" | 210 lbs | - |
| Smith, Cam | 3B | Sugar Land Space Cowboys | 22 | 02/22/2003 | Lake Worth | USA | Right | Right | 6' 3" | 225 lbs | - |
| Sosa, Listher | RP | Reno Aces | 23 | 09/06/2001 | La Vega | DOM | Right | Right | 6' 4" | 205 lbs | - |
| Stassi, Max | C | Sacramento River Cats | 33 | 03/15/1991 | Woodland | USA | Right | Right | 5' 10" | 200 lbs | - |
| Stephan, Josh | SP | Round Rock Express | 23 | 11/01/2001 | Grand Prairie | USA | Right | Right | 6' 3" | 185 lbs | - |
| Sterner, Justin | RP | Las Vegas Aviators | 28 | 08/29/1996 | San Diego | USA | Right | Right | 6' 1" | 215 lbs | - |
| Strahm, Kellen | CF | Round Rock Express | 27 | 04/25/1997 | Eugene | USA | Right | Right | 6' 0" | 215 lbs | - |
| Strickland, Hunter | RP | Free Agent | 36 | 09/24/1988 | Thomaston | USA | Right | Right | 6' 3" | 225 lbs | - |
| Sugastey, Adrian | C | Sacramento River Cats | 22 | 10/23/2002 | Porlamar | VEN | Right | Right | 6' 1" | 210 lbs | - |
| Susac, Daniel | C | Las Vegas Aviators | 23 | 05/14/2001 | Roseville | USA | Right | Right | 6' 4" | 220 lbs | - |
| Swanson, Nic | RP | Sugar Land Space Cowboys | 25 | 07/08/1999 | Bixby | USA | Right | Right | 6' 2" | 180 lbs | - |
