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| Name | Pos | Team | Age | DOB | POB | Nationality | Bats | Throws | Height | Weight | Salary |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Salas, Jose | LF | Cedar Rapids Kernels | 21 | 04/26/2003 | Kissimmee | USA | Switch | Right | 6' 2" | 180 lbs | - |
| Salazar, Johnfrank | 3B | Peoria Chiefs | 21 | 08/05/2003 | Barcelona | VEN | Right | Right | 6' 1" | 160 lbs | - |
| Sales, RJ | SP | West Michigan Whitecaps | 21 | 07/22/2003 | Pinehurst | USA | Right | Right | 6' 0" | 165 lbs | - |
| Salon, Dionmy | C | Quad Cities River Bandits | 23 | 11/18/2001 | Barquisimeto | VEN | Right | Right | 6' 2" | 190 lbs | - |
| Sanabria, Jose | 2B | Fort Wayne TinCaps | 22 | 10/30/2002 | La Victoria | VEN | Right | Right | 5' 10" | 150 lbs | - |
| Sanchez, Edwin | LF | Great Lakes Loons | 20 | 08/02/2004 | Santo Domingo | DOM | Right | Right | 6' 3" | 180 lbs | - |
| Sanchez, Franklin | RP | Beloit Sky Carp | 24 | 09/12/2000 | Jimaní | DOM | Right | Right | 6' 6" | 185 lbs | - |
| Sanchez, Samuel | SP | Great Lakes Loons | 19 | 10/21/2005 | El Tocuyo | VEN | Right | Right | 5' 11" | 150 lbs | - |
| Sando, Nick | RP | Dayton Dragons | 24 | 01/01/2001 | Carlsbad | USA | Left | Left | 6' 2" | 185 lbs | - |
| Santana, Cristian | 2B | West Michigan Whitecaps | 21 | 11/25/2003 | Azua | DOM | Right | Right | 5' 11" | 165 lbs | - |
| Santos, Nolan | SP | Cedar Rapids Kernels | 24 | 12/07/2000 | Miami Beach | USA | Right | Right | 6' 1" | 205 lbs | - |
| Schofield-Sam, T.J. | 3B | Free Agent | 23 | 06/20/2001 | Brampton | CAN | Left | Right | 6' 1" | 185 lbs | - |
| Schwartz, Nick | C | Lansing Lugnuts | 24 | 03/07/2001 | Massapequa | USA | Right | Right | 5' 11" | 180 lbs | - |
| Scott, Kyle | RP | Lake County Captains | 22 | 04/16/2002 | Westminster | USA | Right | Right | 6' 1" | 220 lbs | - |
| Sechrist, Zander | SP | Cedar Rapids Kernels | 23 | 03/14/2002 | Buford | USA | Right | Left | 6' 2" | 175 lbs | - |
| Sellinger, Jack | RP | Beloit Sky Carp | 25 | 11/20/1999 | Las Vegas | USA | Right | Left | 6' 3" | 215 lbs | - |
| Seppings, Jack | RP | Wisconsin Timber Rattlers | 22 | 07/03/2002 | Newnan | USA | Right | Right | 6' 1" | 160 lbs | - |
| Serrano, Jose | 3B | Dayton Dragons | 21 | 10/14/2003 | San Fernando | VEN | Right | Right | 6' 0" | 180 lbs | - |
| Shears, Tanner | RP | Wisconsin Timber Rattlers | 25 | 06/20/1999 | Modesto | USA | Right | Right | 6' 3" | 205 lbs | - |
| Sirota, Mike | LF | Great Lakes Loons | 21 | 06/16/2003 | New York | USA | Right | Right | 6' 2" | 175 lbs | - |
| Sisneros, Cameron | 1B | South Bend Cubs | 23 | 06/01/2001 | Littleton | USA | Left | Left | 6' 2" | 230 lbs | - |
| Sloan, Ethan | CL | West Michigan Whitecaps | 22 | 08/04/2002 | Denver | USA | Left | Left | 5' 11" | 190 lbs | - |
| Smeltz, Jackson | RP | Fort Wayne TinCaps | 26 | 09/14/1998 | Lafayette | USA | Left | Left | 6' 3" | 210 lbs | - |
| Smith, Myles | CF | Dayton Dragons | 22 | 07/09/2002 | Inglewood | USA | Left | Right | 6' 1" | 205 lbs | - |
| Smith, Russell | RP | Free Agent | 26 | 09/10/1998 | Midlothian | USA | Left | Left | 6' 7" | 255 lbs | - |
| Smith, Travis | SP | Wisconsin Timber Rattlers | 22 | 11/09/2002 | Walton | USA | Right | Right | 6' 4" | 220 lbs | - |
| Smith, Tristan | SP | Dayton Dragons | 21 | 05/25/2003 | Chesnee | USA | Right | Left | 6' 2" | 200 lbs | - |
| Snider, Jake | LF | Free Agent | 26 | 05/19/1998 | Champaign | USA | Left | Right | 5' 10" | 190 lbs | - |
| Spears, Brayden | RP | South Bend Cubs | 24 | 02/27/2001 | Brentwood | USA | Right | Right | 6' 6" | 225 lbs | - |
| Spohn, Harrison | SS | Beloit Sky Carp | 26 | 12/03/1998 | Upland | USA | Right | Right | 6' 1" | 200 lbs | - |
| Sprague-Lott, Jared | 3B | Lansing Lugnuts | 23 | 10/10/2001 | Philadelphia | USA | Right | Right | 6' 0" | 195 lbs | - |
| Stankiewicz, John | RP | Cedar Rapids Kernels | 26 | 09/08/1998 | Cherry Hill | USA | Right | Right | 6' 4" | 230 lbs | - |
| Stephan, Anthony | LF | Dayton Dragons | 22 | 12/16/2002 | Ridgewood | USA | Left | Right | 5' 11" | 195 lbs | - |
| Stofel, Luke | SP | West Michigan Whitecaps | 23 | 11/25/2001 | Lawrenceburg | USA | Switch | Right | 6' 4" | 230 lbs | - |
| Stovall, Peyton | 1B | Dayton Dragons | 22 | 02/14/2003 | Haughton | USA | Left | Right | 6' 0" | 185 lbs | - |
| Strong, Jackson | RF | West Michigan Whitecaps | 21 | 08/26/2003 | West Seneca | USA | Left | Left | 6' 1" | 185 lbs | - |
| Stuhr, Sam | CL | Lansing Lugnuts | 22 | 08/08/2002 | Portland | USA | Right | Right | 6' 1" | 200 lbs | - |
| Suarez, Jose | RF | Peoria Chiefs | 20 | 08/09/2004 | Baní | DOM | Right | Right | 6' 3" | 200 lbs | - |
| Sublette, Ryan | RP | Great Lakes Loons | 26 | 10/01/1998 | Lemont | USA | Right | Right | 6' 2" | 190 lbs | - |
| Suriel, Anderson | RF | South Bend Cubs | 21 | 04/11/2003 | Santo Domingo | DOM | Left | Left | 6' 1" | 175 lbs | - |
| Swilling, Carson | SP | Fort Wayne TinCaps | 23 | 01/09/2002 | Smiths Station | USA | Right | Right | 6' 1" | 185 lbs | - |
